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Label-free Biomedical Imaging and Sensing (LBIS) 2020


Date & time 1 Feb
Event ends 6 Feb
US, California
San Francisco
The Moscone Center
Creator Biophotonics.World

Who's attending



Label-free Biomedical Imaging and Sensing (LBIS) 2020

Call for abstracts!! Please submit your abstracts until July 24. We are looking forward to many submissions!

Label-free biomedical optical imaging and sensing refers to optical measurements performed on biological samples or living organisms without the need for utilizing labeling agents. Label-free imaging of cells in vitro is specifically of interest, since isolated cells are optically transparent and regular bright-field imaging does not present enough imaging contrast. Labeling agents, such as fluorescent dyes or labels using antibodies, can create molecular specificity and enhance contrast but they might interfere with the biological phenomena measured, and thus are not always allowed. In addition, some biological targets do not have suitable labeling agents. In vivo imaging of living organisms, and humans in particular, should be preferably performed without using labeling agents, due to possible hazardous effects induced by these agents. 

Optical detection methods for label-free imaging and sensing are typically based on internal contrast mechanisms of the sample; for example, its ability to delay the light interacting with the sample due to refractive index changes, or its ability to create unique optical spectroscopic, auto-fluorescence, or birefringence or acoustic signatures. In addition, the substrate holding the sample during measurement can be used to enhance the detection and monitor of the sample properties via various effects, including Plasmon resonance, total internal reflection, etc. Furthermore, life science tools, such as optogenetics or gene expression methods, can be applied to achieve molecular specificity in living objects. 

Label-free imaging and sensing in the nanoscale, including tracking of single molecules, is of high interest as well. Specifically, label-free optical nanoscopy is still considered as an unsolved challenge in this field. 

This conference will gather scientists from various disciplines, who are interested in optical imaging and sensing of biological substances without using labeling: physicists and engineers on the one hand, chemists and life scientists performing optical label-free sensing on the other hand. Keynote presentations for 2020 include:
  • Aydogan Ozcan, Univ. of California, Los Angeles (United States) presenting Deep learning-enabled holography
  • Jürgen Popp, Leibniz-Institut für Photonische Technologien e.V. (Germany) presenting Rapid theranostics by multicontast spectroscopy/imaging
  • Ji-Xin Cheng, Boston Univ. (United States) presentation title to be determined
  • Guillermo J. Tearney, Massachusetts Institute of Technology (United States) presentation title to be determined

Relevant topics include, but are not limited to: 
  • Phase imaging (Zernike’s, differential interference contrast (DIC), holography, optical diffraction tomography (ODT), etc.)
  • Coherent vibrational scattering techniques (CARS/SRS)
  • Spontaneous Raman imaging
  • Interferometric and coherence gated imaging (optical coherence tomography, etc.)
  • Polarization and birefringence imaging
  • Dark-field microscopy
  • Brillouin microscopy (spontaneous and stimulated)
  • High harmonic generation and nonlinear imaging and sensing
  • Auto-fluorescence imaging and sensing
  • Hyperspectral imaging and sensing
  • Total internal reflection imaging and sensing
  • Acoustic and photoacoustic imaging
  • Plasmonic sensors
  • Fiber-optics-based label-free bio-detectors
  • Label-free imaging in the nano-scale
  • On-chip implementations of label-free sensors
  • Preclinical, clinical, and life science applications
  • Label-free imaging using optogenetic and gene expression tools.
Area of application: Dentistry , Dermatology, Gastroenterology, Gynecology and Obstetrics, Human genetics, Infectious disease and antibiotic resistance, Internal medicine and general medicine, Laboratory and environmental medicine, Neurology, Neurosurgery, Oncology, Ophthalmology Diagnostics and Imaging, Otorhinolaryngology, Pathology, Pediatrics and Neonatology, Pharmacology, Pulmonology, Reproductive Medicine, Rheumatology, Surgery, Urology and Nephrology, Medicine, other applications, Cellular biotechnology, Drug delivery, Molecular diagnostics, Pharmaceuticals (development, production, monitoring), Therapeutics, Tissue enginieering, Health, other applications, Biochemistry, Cell Biology, Developmental biology, Ecology, Genetics, Human biology, Microbiology, Molecular biology, Physiology, Biology, other applications
Methods and Techniques: Endoscopy, General microscopy (white light, confocal, bright field, dark field, phase contrast, DIC etc.), Linear and non-linear fluorescence imaging (confocal LSM, multi-photon, STED, PALM, STORM, SIM, FRET, FRAP, FLIM, etc.), Linear and non-linear vibrational microscopy / imaging (IR, confocal Raman, CARS, SRS etc.), Near-field microscopy (SNOM, AFM, STM, etc.), Optical Coherence Tomography (OCT ), Operating microscopy, Photoacoustic imaging (PAI, MSOT), Polarimetry, Probe and sensor development, Terahertz imaging, Thermography, Microscopy/Imaging, other methods and techniques, ATR / FTIR Spectroscopy, Coherent Back Scattering CBS, Diffuse Optics, Dynamic Light Scattering DLS, Ellipsometry, Fluorescence spectroscopy, Photoluminescence, Reflectance, Terahertz spectroscopy, UV / VIS spectroscopy, Vibrational spectroscopy (Raman, Infrared), Spectroscopy, other methods and techniques, CCD and CMOS sensors and cameras, Fiber optical illumination, Functionalized fibres, Implant manufacturing, Laser , Laser-induced microdissection and catapulting of cells, Laser micromanipulation, Microstructure Fibers, Objectives, Optical clearing, Optical tweezers, Tissue separation / laser scalpels, Enabling Technologies, other methods and techniques