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Call for Papers: Label-free Biomedical Imaging and Sensing #LBIS2019

23 Jul | By Biophotonics.World
Call for Papers: Label-free Biomedical Imaging and Sensing #LBIS2019
Image source: SPIE

The conference refers to optical measurements performed on biological samples or living organisms without the need for utilizing labeling agents. Label-free imaging of cells in vitro is specifically of interest, since isolated cells are optically transparent and regular bright-field imaging does not present enough imaging contrast. Labeling agents, such as fluorescent dyes or labels using antibodies, can help create molecular specificity and enhance contrast but they are sometimes cytotoxic, or might interfere with the biological phenomena measured, and thus are not always allowed. In addition, some biological targets do not have suitable labeling agents. In vivo imaging of living organisms, and humans in particular, should be preferably performed without using labeling agents, due to possible hazardous effects induced by these agents.


LBIS2019  is part of the Photonics West an will take place in San Francisco (2 - 7 February 2019). 
This conference has an open call for papers. Please use the online submission form on the Phtoniocs West website (https://spie.org/PWB/conferencedetails/label-free-biomedical-imaging-and-sensing?SSO=1)


Optical detection methods for label-free imaging and sensing are typically based on internal contrast mechanisms of the sample; for example, its ability to delay the light interacting with it due to refractive index changes, or its ability to create unique optical spectroscopic, auto-fluorescence, or birefringence signatures. In addition, the substrate holding the sample during measurement can be used to enhance the detection and monitor of the sample properties via various effects, including Plasmon resonance, total internal reflection, etc. Furthermore, life science tools, such as optogenetics or gene expression methods, can be applied to achieve molecular specificity in living objects. 


Label-free imaging and sensing in the nanoscale, including tracking of single molecules, is of high interest as well. Specifically, label-free optical nanoscopy is still considered as an unsolved challenge in this field. 


This conference will gather scientists from various disciplines, who are interested in optical imaging and sensing of biological substances without using labeling: physicists and engineers on the one hand, chemist and life scientist performing optical label-free sensing on the other hand. Keynote presentations for 2019 include: 

X. Sunney Xie, Peking Univ. (China) presenting Stimulated Raman scattering microscopy: label-free vibrational imaging for biology and medicine

Lihong V. Wang, Caltech (United States) presenting World’s deepest-penetration and fastest cameras: photoacoustic tomography and compressed ultrafast photography

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